c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells.
We studied the effects of transfection of the normal c-Ha-ras gene, rasGly-12, and its oncogenic mutant, rasVal-12, on expression of the alpha-fetoprotein (AFP) and albumin genes in a human hepatoma cell line, HuH-7. The mutant and, to a lesser extent, the normal ras gene caused reduction of the AFP...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1690841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1461-1469.1990 |
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