c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells.

We studied the effects of transfection of the normal c-Ha-ras gene, rasGly-12, and its oncogenic mutant, rasVal-12, on expression of the alpha-fetoprotein (AFP) and albumin genes in a human hepatoma cell line, HuH-7. The mutant and, to a lesser extent, the normal ras gene caused reduction of the AFP...

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Detalhes bibliográficos
Main Authors: Nakao, K, Lawless, D, Ohe, Y, Miyao, Y, Nakabayashi, H, Kamiya, H, Miura, K, Ohtsuka, E, Tamaoki, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC362248/
https://ncbi.nlm.nih.gov/pubmed/1690841
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