Ouabain-resistant mutants of the rat Na,K-ATPase alpha 2 isoform identified by using an episomal expression vector.

Site-directed mutagenesis was used to identify residues responsible for the greater than 1,000-fold difference in ouabain sensitivity between the rat Na,K-ATPase alpha 1 and alpha 2 isoforms. A series of mutagenized cDNAs was constructed that replaced residues of the rat alpha 2 subunit with the cor...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Canfield, V, Emanuel, J R, Spickofsky, N, Levenson, R, Margolskee, R F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157137/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1367-1372.1990
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