Rho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acid

We previously reported that lysophosphatidic acid (LPA) inhibits the neuronal differentiation of human embryonic stem cells (hESC). We extended these studies by analyzing LPA's effects on the expansion of neural stem/progenitor cells (NS/PC) derived from hESCs and human induced pluripotent stem...

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Main Authors: Frisca, Frisca, Crombie, Duncan E., Dottori, Mirella, Goldshmit, Yona, Pébay, Alice
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622317/
https://ncbi.nlm.nih.gov/pubmed/23463731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M032284
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