Rho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acid

We previously reported that lysophosphatidic acid (LPA) inhibits the neuronal differentiation of human embryonic stem cells (hESC). We extended these studies by analyzing LPA's effects on the expansion of neural stem/progenitor cells (NS/PC) derived from hESCs and human induced pluripotent stem...

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Main Authors: Frisca, Frisca, Crombie, Duncan E., Dottori, Mirella, Goldshmit, Yona, Pébay, Alice
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2013
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622317/
https://ncbi.nlm.nih.gov/pubmed/23463731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M032284
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