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One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli
BACKGROUND: Human α-synuclein is a small-sized, natively unfolded protein that in fibrillar form is the primary component of Lewy bodies, the pathological hallmark of Parkinson’s disease. Experimental evidence suggests that α-synuclein aggregation is the key event that triggers neurotoxicity althoug...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621789/ https://ncbi.nlm.nih.gov/pubmed/23557146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-32 |
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