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Optimizing HIV-1 protease production in Escherichia coli as fusion protein

BACKGROUND: Human immunodeficiency virus (HIV) is the etiological agent in AIDS and related diseases. The aspartyl protease encoded by the 5' portion of the pol gene is responsible for proteolytic processing of the gag-pol polyprotein precursor to yield the mature capsid protein and the reverse...

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Detalhes bibliográficos
Main Authors: Volontè, Federica, Piubelli, Luciano, Pollegioni, Loredano
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141379/
https://ncbi.nlm.nih.gov/pubmed/21718537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-53
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