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Centrosomes, chromosome instability (CIN) and aneuploidy

Each time a cell divides its chromosome content must be equally segregated into the two daughter cells. This critical process is mediated by a complex microtubule based apparatus, the mitotic spindle. In most animal cells the centrosomes contribute to the formation and the proper function of the mit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Vitre, Benjamin D., Cleveland, Don W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621708/
https://ncbi.nlm.nih.gov/pubmed/23127609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2012.10.006
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