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Trypanocidal activity of salinomycin is due to sodium influx followed by cell swelling

BACKGROUND: The few currently available drugs for treatment of African trypanosomiasis are outdated and show problems with toxicity and resistance. Hence, there is an urgent need for the discovery and development of new anti-trypanosomal agents. FINDINGS: In this study, the ionophorous antibiotic sa...

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Detaylı Bibliyografya
Asıl Yazarlar: Steverding, Dietmar, Sexton, Darren W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621689/
https://ncbi.nlm.nih.gov/pubmed/23517602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-6-78
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