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Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei

[Image: see text] The protozoan parasite Trypanosoma brucei is the causative agent of African sleeping sickness, and there is an urgent unmet need for improved treatments. Parasite protein kinases are attractive drug targets, provided that the host and parasite kinomes are sufficiently divergent to...

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Κύριοι συγγραφείς: Urbaniak, Michael D., Mathieson, Toby, Bantscheff, Marcus, Eberhard, Dirk, Grimaldi, Raffaella, Miranda-Saavedra, Diego, Wyatt, Paul, Ferguson, Michael A. J., Frearson, Julie, Drewes, Gerard
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Chemical Society 2012
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621575/
https://ncbi.nlm.nih.gov/pubmed/22908928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300326z
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