Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei

[Image: see text] The protozoan parasite Trypanosoma brucei is the causative agent of African sleeping sickness, and there is an urgent unmet need for improved treatments. Parasite protein kinases are attractive drug targets, provided that the host and parasite kinomes are sufficiently divergent to...

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Auteurs principaux: Urbaniak, Michael D., Mathieson, Toby, Bantscheff, Marcus, Eberhard, Dirk, Grimaldi, Raffaella, Miranda-Saavedra, Diego, Wyatt, Paul, Ferguson, Michael A. J., Frearson, Julie, Drewes, Gerard
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2012
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621575/
https://ncbi.nlm.nih.gov/pubmed/22908928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300326z
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