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De novo lumen formation and elongation in the developing nephron: a central role for afadin in apical polarity

A fundamental process in biology is the de novo formation and morphogenesis of polarized tubules. Although these processes are essential for the formation of multiple metazoan organ systems, little is known about the molecular mechanisms that regulate them. In this study, we have characterized sever...

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Detalhes bibliográficos
Main Authors: Yang, Zhufeng, Zimmerman, Susan, Brakeman, Paul R., Beaudoin, Gerard M., Reichardt, Louis F., Marciano, Denise K.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621492/
https://ncbi.nlm.nih.gov/pubmed/23487309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087957
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