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Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis

Proper lumen morphogenesis during pancreas development is critical to endocrine and exocrine cell fate. Recent studies showed that a central network of lumens (termed core), but not the surrounding terminal branches (termed periphery), produces most islet endocrine cells. To date, it remains unclear...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Azizoglu, D. Berfin, Braitsch, Caitlin, Marciano, Denise K., Cleaver, Ondine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795784/
https://ncbi.nlm.nih.gov/pubmed/29330353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.307637.117
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