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Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis
Proper lumen morphogenesis during pancreas development is critical to endocrine and exocrine cell fate. Recent studies showed that a central network of lumens (termed core), but not the surrounding terminal branches (termed periphery), produces most islet endocrine cells. To date, it remains unclear...
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Publicado no: | Genes Dev |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5795784/ https://ncbi.nlm.nih.gov/pubmed/29330353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.307637.117 |
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