Φορτώνει......
Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification
The core gene regulatory network (GRN) in embryonic stem cells (ESCs) integrates activities of the pro-self-renewal factors Oct4 (Pou5f1), Sox2 and Nanog with that of an inhibitor of self-renewal, Tcf7l1 (Tcf3). The inhibitor function of Tcf7l1 causes dependence on extracellular Wnt/β-catenin signal...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Company of Biologists
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621485/ https://ncbi.nlm.nih.gov/pubmed/23487311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087387 |
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