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Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit
Correct execution of mitosis in eukaryotes relies on timely activation and inactivation of cyclin B-dependent kinase 1 (cdk1), the M-phase-promoting factor (MPF). Once activated, MPF is sustained until mitotic spindle assembly by phosphorylation-dependent feedback loops that prevent inhibitory phosp...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621406/ https://ncbi.nlm.nih.gov/pubmed/22692537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1886 |
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