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Mechanism of activation of the human trk oncogene.

The human trk oncogene was generated by a genetic rearrangement that replaced the extracellular domain of the normal trk tyrosine kinase receptor by sequences coding for the 221 amino-terminal residues of a nonmuscle tropomyosin. Molecular dissection of a cDNA clone of the trk oncogene indicated tha...

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Autors principals: Coulier, F, Martin-Zanca, D, Ernst, M, Barbacid, M
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC362140/
https://ncbi.nlm.nih.gov/pubmed/2538716
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