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Frequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences.
Transfection of NIH 3T3 cells with cDNA clones containing either the entire coding sequences or the tyrosine protein kinase domain of the human TRK protooncogene results in the frequent generation of transforming genes. Activation of most of these TRK oncogenes involves acquisition of DNA sequences....
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3362859/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.2964 |
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