Frequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences.

Transfection of NIH 3T3 cells with cDNA clones containing either the entire coding sequences or the tyrosine protein kinase domain of the human TRK protooncogene results in the frequent generation of transforming genes. Activation of most of these TRK oncogenes involves acquisition of DNA sequences....

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Oskam, R, Coulier, F, Ernst, M, Martin-Zanca, D, Barbacid, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3362859/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.2964
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