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Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene.

Nerve growth factor (NGF) promotes the survival and differentiation of specific populations of neurons. The molecular mechanisms by which cells respond to NGF are poorly understood, but two clues have emerged recently. First, NGF rapidly stimulates tyrosine phosphorylation of several unidentified pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Vetter, M L, Martin-Zanca, D, Parada, L F, Bishop, J M, Kaplan, D R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51935/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5650
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