PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

Based on the fact that aging is associated with a reciprocal decrease of osteogenesis and an increase of adipogenesis in bone marrow and that osteoblasts and adipocytes share a common progenitor, this study investigated the role of PPARγ, a key regulator of adipocyte differentiation, in bone metabol...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Akune, Toru, Ohba, Shinsuke, Kamekura, Satoru, Yamaguchi, Masayuki, Chung, Ung-il, Kubota, Naoto, Terauchi, Yasuo, Harada, Yoshifumi, Azuma, Yoshiaki, Nakamura, Kozo, Kadowaki, Takashi, Kawaguchi, Hiroshi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2004
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15067317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19900
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