Benzamidine derivatives inhibit the virulence of Porphyromonas gingivalis

We have previously shown that benzamidine-type compoundscan inhibit the activity of arginine-specific cysteine proteinases (gingipainsHRgpA and RgpB); well-known virulence factors of Porphyromonas gingivalis. They also hinder in vitro growth of this important period on to pathogenic bacterium. Appar...

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Bibliographic Details
Main Authors: Fröhlich, Esther, Kantyka, Tomasz, Plaza, Karolina, Schmidt, Karl-Hermann, Pfister, Wolfgang, Potempa, Jan, Eick, Sigrun
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620930/
https://ncbi.nlm.nih.gov/pubmed/23279840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12015
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