Cleavage of IgG1 in GCF is associated with presence of Porphyromonas gingivalis

BACKGROUND AND OBJECTIVES: Immunoglobulin (Ig) G1 plays an important role in the adaptive immune response. Kgp, a lysine-specific cysteine protease from Porphyromonas gingivalis, specifically hydrolyses IgG1 heavy chains. The purpose of this study was to examine whether cleavage of IgG1 occurs in gi...

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Detalhes bibliográficos
Main Authors: Guentsch, Arndt, Hirsch, Christiane, Pfister, Wolfgang, Vincents, Bjarne, Abrahamson, Magnus, Sroka, Aneta, Potempa, Jan, Eick, Sigrun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566341/
https://ncbi.nlm.nih.gov/pubmed/23116446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jre.12027
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