Gingipains of Porphyromonas gingivalis Affect the Stability and Function of Serine Protease Inhibitor of Kazal-type 6 (SPINK6), a Tissue Inhibitor of Human Kallikreins

Periodontitis, a chronic inflammation driven by dysbiotic subgingival bacterial flora, is linked on clinical levels to the development of a number of systemic diseases and to the development of oral and gastric tract tumors. A key pathogen, Porphyromonas gingivalis, secretes gingipains, cysteine pro...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Plaza, Karolina, Kalinska, Magdalena, Bochenska, Oliwia, Meyer-Hoffert, Ulf, Wu, Zhihong, Fischer, Jan, Falkowski, Katherine, Sasiadek, Laura, Bielecka, Ewa, Potempa, Barbara, Kozik, Andrzej, Potempa, Jan, Kantyka, Tomasz
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009250/
https://ncbi.nlm.nih.gov/pubmed/27354280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722942
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