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O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia

The development of resistance to chemotherapy is a major cause of relapse in acute lymphoblastic leukemia (ALL). Though several mechanisms associated with drug resistance have been studied in detail, the role of carbohydrate modification remains unexplored. Here, we investigated the contribution of...

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Detalhes bibliográficos
Main Authors: Parameswaran, Reshmi, Lim, Min, Arutyunyan, Anna, Abdel-Azim, Hisham, Hurtz, Christian, Lau, Kam, Müschen, Markus, Yu, Robert K., von Itzstein, Mark, Heisterkamp, Nora, Groffen, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620349/
https://ncbi.nlm.nih.gov/pubmed/23478187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121482
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