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Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist
The bone marrow (BM) stromal niche can protect acute lymphoblastic leukemia (ALL) cells against the cytotoxicity of chemotherapeutic agents and is a possible source of relapse. The SDF-1/CXCR4 axis is a major determinant in the crosstalk between leukemic cells and BM stroma. In the current study, we...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135709/ https://ncbi.nlm.nih.gov/pubmed/21483439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.76 |
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