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Anti-Thy-1 Antibody-mediated Complement-dependent Cytotoxicity is Regulated by the Distribution of Antigen, Antibody and Membrane Complement Regulatory Proteins in Rats

Some therapeutic antibodies as anticancer agents exert their effects through the host immune system, but the factors that predict their cytotoxicity, including complement-dependent cytotoxicity (CDC), are unclear. In the present study, we attempted to elucidate some of these factors in a preclinical...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kato, Chie, Kato, Atsuhiko, Adachi, Kenji, Fujii, Etsuko, Isobe, Kaori, Matsushita, Tomochika, Watanabe, Takeshi, Suzuki, Masami
التنسيق: Artigo
اللغة:Inglês
منشور في: Japanese Society of Toxicologic Pathology 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620213/
https://ncbi.nlm.nih.gov/pubmed/23723567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.26.41
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