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Anti-Thy-1 Antibody-mediated Complement-dependent Cytotoxicity is Regulated by the Distribution of Antigen, Antibody and Membrane Complement Regulatory Proteins in Rats

Some therapeutic antibodies as anticancer agents exert their effects through the host immune system, but the factors that predict their cytotoxicity, including complement-dependent cytotoxicity (CDC), are unclear. In the present study, we attempted to elucidate some of these factors in a preclinical...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kato, Chie, Kato, Atsuhiko, Adachi, Kenji, Fujii, Etsuko, Isobe, Kaori, Matsushita, Tomochika, Watanabe, Takeshi, Suzuki, Masami
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Japanese Society of Toxicologic Pathology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620213/
https://ncbi.nlm.nih.gov/pubmed/23723567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.26.41
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