NADH Oxidase Functions as an Adhesin in Streptococcus pneumoniae and Elicits a Protective Immune Response in Mice

The initial event in disease caused by S. pneumoniae is adhesion of the bacterium to respiratory epithelial cells, mediated by surface expressed molecules including cell-wall proteins. NADH oxidase (NOX), which reduces free oxygen to water in the cytoplasm, was identified in a non-lectin enriched pn...

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Hauptverfasser: Muchnik, Lena, Adawi, Asad, Ohayon, Ariel, Dotan, Shahar, Malka, Itai, Azriel, Shalhevet, Shagan, Marilou, Portnoi, Maxim, Kafka, Daniel, Nahmani, Hannie, Porgador, Angel, Gershoni, Johnatan M., Morrison, Donald A., Mitchell, Andrea, Tal, Michael, Ellis, Ronald, Dagan, Ron, Nebenzahl, Yaffa Mizrachi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620118/
https://ncbi.nlm.nih.gov/pubmed/23577197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061128
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