Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge

Pneumococcal flavin reductase (FlaR) is known to be cell-wall associated and possess age dependent antigenicity in children. This study aimed at characterizing FlaR and elucidating its involvement in pneumococcal physiology and virulence. Bioinformatic analysis of FlaR sequence identified three-cons...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Morozov, Giora I., Porat, Nurith, Kushnir, Tatyana, Najmuldeen, Hastyar, Adawi, Asad, Chalifa-Caspi, Vered, Benisty, Rachel, Ohayon, Ariel, Liron, Ofir, Azriel, Shalhevet, Malka, Itai, Dotan, Shahar, Portnoi, Maxim, Piotrowski, Andrew A., Kafka, Daniel, Hajaj, Barak, Fishilevich, Tali, Shagan, Marilou, Tal, Michael, Ellis, Ron, Morrison, Donald A., Mitchell, Andrea M., Mitchell, Timothy J., Dagan, Ron, Yesilkaya, Hasan, Nebenzahl, Yaffa Mizrachi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762878/
https://ncbi.nlm.nih.gov/pubmed/29321514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18645-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky