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Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine

In Streptococcus pneumonia, phosphoenolpyruvate protein phosphotransferase (PtsA) is an intracellular protein of the monosaccharide phosphotransferase systems. Biochemical and immunostaining methods were applied to show that PtsA also localizes to the bacterial cell-wall. Thus, it was suspected that...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mizrachi Nebenzahl, Yaffa, Blau, Karin, Kushnir, Tatyana, Shagan, Marilou, Portnoi, Maxim, Cohen, Aviad, Azriel, Shalhevet, Malka, Itai, Adawi, Asad, Kafka, Daniel, Dotan, Shahar, Guterman, Gali, Troib, Shany, Fishilevich, Tali, Gershoni, Jonathan M, Braiman, Alex, Mitchell, Andrea M, Mitchell, Timothy J, Porat, Nurith, Goliand, Inna, Chalifa Caspi, Vered, Swiatlo, Edwin, Tal, Michael, Ellis, Ronald, Elia, Natalie, Dagan, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798226/
https://ncbi.nlm.nih.gov/pubmed/26990554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150320
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