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Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles

Lysosome-related organelles (LROs) exist in specialized cells to serve specific functions and typically co-exist with conventional lysosomes. The biogenesis of LROs is known to utilize much of the common protein machinery used in the transport of integral membrane proteins to lysosomes. Consequently...

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Bibliographic Details
Main Authors: Bultema, Jarred J., Di Pietro, Santiago M.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620096/
https://ncbi.nlm.nih.gov/pubmed/23247405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.22349
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