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Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles

Lysosome-related organelles (LROs) exist in specialized cells to serve specific functions and typically co-exist with conventional lysosomes. The biogenesis of LROs is known to utilize much of the common protein machinery used in the transport of integral membrane proteins to lysosomes. Consequently...

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Autori principali: Bultema, Jarred J., Di Pietro, Santiago M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620096/
https://ncbi.nlm.nih.gov/pubmed/23247405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.22349
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