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Organelle biogenesis: En BLOC exchange for RAB32 and RAB38

Prominent subtypes of the genetic disorder, Hermansky-Pudlak Syndrome, result from defects in a mysterious protein complex, BLOC-3. New work identifies BLOC-3 as a guanine nucleotide exchange factor for two Rab GTPases previously implicated in lysosome-related organelle biogenesis.

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Dades bibliogràfiques
Autor principal: Marks, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513372/
https://ncbi.nlm.nih.gov/pubmed/23174301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.10.005
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