Assembly of the Biogenesis of Lysosome-related Organelles Complex-3 (BLOC-3) and Its Interaction with Rab9

The Hermansky-Pudlak syndrome (HPS) is a genetic hypopigmentation and bleeding disorder caused by defective biogenesis of lysosome-related organelles (LROs) such as melanosomes and platelet dense bodies. HPS arises from mutations in any of 8 genes in humans and 16 genes in mice. Two of these genes,...

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Detalhes bibliográficos
Main Authors: Kloer, Daniel P., Rojas, Raul, Ivan, Viorica, Moriyama, Kengo, van Vlijmen, Thijs, Murthy, Namita, Ghirlando, Rodolfo, van der Sluijs, Peter, Hurley, James H., Bonifacino, Juan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844223/
https://ncbi.nlm.nih.gov/pubmed/20048159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069088
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