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A constitutively active Gα subunit provide insights into the mechanism of G protein activation
The activation of Gα subunits of heterotrimeric G proteins by G protein-coupled receptors (GPCRs) is a critical event underlying a variety of biological responses. Understanding how G proteins are activated will require structural and biochemical analyses of GPCRs complexed to their G protein partne...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620018/ https://ncbi.nlm.nih.gov/pubmed/22448927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3001984 |
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