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PU.1-Dependent Transcriptional Regulation of miR-142 Contributes to Its Hematopoietic Cell–Specific Expression and Modulation of IL-6

MicroRNAs (miRs) have emerged as critical modulators of immune responses, but little is known about their transcriptional regulation and tissue specificity. miR-142 is specifically expressed in hematopoietic tissues and plays an important role in regulating immunity. In this study we identified the...

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Detalhes bibliográficos
Main Authors: Sun, Yaping, Sun, John, Tomomi, Toubai, Nieves, Evelyn, Mathewson, Nathan, Tamaki, Hiroya, Evers, Rebecca, Reddy, Pavan
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619529/
https://ncbi.nlm.nih.gov/pubmed/23509362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202911
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