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Donor- but not host-derived interleukin-10 contributes to the regulation of experimental graft-versus-host disease
IL-10 is a key immune-regulatory cytokine, and its gene polymorphisms correlate with severity of clinical GVHD. IL-10 is made by a variety of donor and host cells, but the functional relevance of its source and its role in the biology of acute GVHD are not well understood. We used preclinical models...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317273/ https://ncbi.nlm.nih.gov/pubmed/22262800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1011510 |
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