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Donor- but not host-derived interleukin-10 contributes to the regulation of experimental graft-versus-host disease

IL-10 is a key immune-regulatory cytokine, and its gene polymorphisms correlate with severity of clinical GVHD. IL-10 is made by a variety of donor and host cells, but the functional relevance of its source and its role in the biology of acute GVHD are not well understood. We used preclinical models...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Tawara, Isao, Sun, Yaping, Liu, Chen, Toubai, Tomomi, Nieves, Evelyn, Evers, Rebecca, Alrubaie, Mariem, Mathewson, Nathan, Tamaki, Hiroya, Reddy, Pavan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Leukocyte Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317273/
https://ncbi.nlm.nih.gov/pubmed/22262800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1011510
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