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Evaluation of polymorphisms in the sulfonamide detoxification genes NAT2, CYB5A, and CYB5R3 in patients with sulfonamide hypersensitivity

OBJECTIVE: To determine whether polymorphisms in the sulfonamide detoxification genes, CYB5A (encoding cytochrome b(5)), CYB5R3 (encoding cytochrome b(5) reductase), or NAT2 (encoding N-acetyltransferase 2) were over-represented in patients with delayed sulfonamide drug hypersensitivity, compared to...

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Detaylı Bibliyografya
Asıl Yazarlar: Sacco, James, Abouraya, Mahmoud, Motsinger-Reif, Alison, Yale, Steven, McCarty, Catherine, Trepanier, Lauren
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619396/
https://ncbi.nlm.nih.gov/pubmed/22850190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328357a735
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