Neonatal antibody responses are attenuated by interferon-γ produced by NK and T cells during RSV infection

Respiratory syncytial virus (RSV) infects most children in the first year of life and is a major single cause of hospitalization in infants and young children. There is no effective vaccine, and antibody generated by primary neonatal infection is poorly protective against reinfection even with antig...

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Autors principals: Tregoning, John S., Wang, Belinda Lei, McDonald, Jacqueline U., Yamaguchi, Yuko, Harker, James A., Goritzka, Michelle, Johansson, Cecilia, Bukreyev, Alexander, Collins, Peter L., Openshaw, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619373/
https://ncbi.nlm.nih.gov/pubmed/23509276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214247110
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