Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating

The discovery of the light-gated ion channel channelrhodopsin (ChR) set the stage for the novel field of optogenetics, where cellular processes are controlled by light. However, the underlying molecular mechanism of light-induced cation permeation in ChR2 remains unknown. Here, we have traced the st...

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Bibliographic Details
Main Authors: Lórenz-Fonfría, Víctor A., Resler, Tom, Krause, Nils, Nack, Melanie, Gossing, Michael, Fischer von Mollard, Gabriele, Bamann, Christian, Bamberg, Ernst, Schlesinger, Ramona, Heberle, Joachim
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619329/
https://ncbi.nlm.nih.gov/pubmed/23509282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219502110
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