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pH-sensitive vibrational probe reveals a cytoplasmic protonated cluster in bacteriorhodopsin

Infrared spectroscopy has been used in the past to probe the dynamics of internal proton transfer reactions taking place during the functional mechanism of proteins but has remained mostly silent to protonation changes in the aqueous medium. Here, by selectively monitoring vibrational changes of buf...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lorenz-Fonfria, Victor A., Saita, Mattia, Lazarova, Tzvetana, Schlesinger, Ramona, Heberle, Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754764/
https://ncbi.nlm.nih.gov/pubmed/29203649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707993114
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