The length of homology required for gene targeting in embryonic stem cells.
Homologous recombination has been used to introduce site-specific mutations into murine embryonic stem (ES) cells with both insertion and replacement vectors. In this study, we compared the frequency of gene targeting with various lengths of homology and found a dramatic increase in targeting with a...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361929/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.11.5586-5591.1991 |
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