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Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts.

Treatment of splenic B lymphocytes and certain B-lineage cell lines with the mitogen lipopolysaccharide (LPS) and the lymphokine interleukin-4 (IL-4) induces expression of germ line immunoglobulin C epsilon transcripts and class switching to the C epsilon gene. We show that LPS-plus-IL-4 induction o...

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Udgivet i:Mol Cell Biol
Principais autores: Rothman, P, Li, S C, Gorham, B, Glimcher, L, Alt, F, Boothby, M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922063/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.11.5551-5561.1991
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