Grail as a molecular determinant for the functions of the tumor suppressor p53 in tumorigenesis

The transcription factor p53 is a multifunctional tumor suppressor that arrests the cell cycle in response to stress and modulates the DNA repair process or induces apoptosis. The cellular level and activity of p53 are tightly controlled to maintain proper functioning. This study identified a novel...

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Detalhes bibliográficos
Main Authors: Chen, Y-C, Chan, J Y-H, Chiu, Y-L, Liu, S-T, Lozano, G, Wang, S-L, Ho, C-L, Huang, S-M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619241/
https://ncbi.nlm.nih.gov/pubmed/23370271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.1
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