miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis

BACKGROUND: Clear cell renal cancer frequently harbours von Hippel–Lindau (VHL) gene mutations, leading to stabilisation of the hypoxia-inducible factors (HIFs) and expression of their target genes. We investigated HIF-1 and HIF-2 in the regulation of microRNA-210 (miR-210), and its clinical relevan...

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Bibliografiske detaljer
Main Authors: McCormick, R I, Blick, C, Ragoussis, J, Schoedel, J, Mole, D R, Young, A C, Selby, P J, Banks, R E, Harris, A L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619073/
https://ncbi.nlm.nih.gov/pubmed/23449350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.56
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