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The Insulin Receptor Negatively Regulates the Action of Pseudomonas Toxin-Based Immunotoxins and Native Pseudomonas Toxin
SS1P is a recombinant immunotoxin composed of an anti-mesothelin Fv fragment fused to a truncated portion of Pseudomonas exotoxin (PE) A. SS1P targets and kills mesothelin-expressing tumors, which include mesothlioma as well as ovarian, lung and pancreatic cancers. SS1P is currently in clinical tria...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618569/ https://ncbi.nlm.nih.gov/pubmed/23348423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3436 |
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