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RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation

Converging signals from the mammalian target of rapamycin (mTOR) and phosphoinositide 3-kinase (PI3K) pathways are well established to modulate translation initiation. Less is known regarding the molecular basis of protein synthesis regulated by other inputs, such as agonists of the Ras/extracellula...

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Detalhes bibliográficos
Main Authors: Roux, Philippe P., Shahbazian, David, Vu, Hieu, Holz, Marina K., Cohen, Michael S., Taunton, Jack, Sonenberg, Nahum, Blenis, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618456/
https://ncbi.nlm.nih.gov/pubmed/17360704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700906200
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