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TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells

TRIM16 exhibits tumour suppressor functions by interacting with cytoplasmic vimentin and nuclear E2F1 proteins in neuroblastoma and squamous cell carcinoma cells, reducing cell migration and replication. Reduced TRIM16 expression in a range of human primary malignant tissues correlates with increase...

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Detalhes bibliográficos
Main Authors: Kim, Patrick Y., Rahmanto, Aldwin Suryo, Tan, Owen, Norris, Murray D., Haber, Michelle, Marshall, Glenn M., Cheung, Belamy B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618413/
https://ncbi.nlm.nih.gov/pubmed/23404198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0813-y
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