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Withaferin A activates TRIM16 for its anti-cancer activity in melanoma

Although selective BRAF inhibitors and novel immunotherapies have improved short-term treatment responses in metastatic melanoma patients, acquired resistance to these therapeutics still represent a major challenge in clinical practice. In this study, we evaluated the efficacy of Withaferin A (WFA),...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nagy, Zsuzsanna, Cheung, Belamy B., Tsang, Wing, Tan, Owen, Herath, Mika, Ciampa, Olivia C., Shadma, Fatima, Carter, Daniel R., Marshall, Glenn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665169/
https://ncbi.nlm.nih.gov/pubmed/33184347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76722-x
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