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TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells

TRIM16 exhibits tumour suppressor functions by interacting with cytoplasmic vimentin and nuclear E2F1 proteins in neuroblastoma and squamous cell carcinoma cells, reducing cell migration and replication. Reduced TRIM16 expression in a range of human primary malignant tissues correlates with increase...

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Détails bibliographiques
Auteurs principaux: Kim, Patrick Y., Rahmanto, Aldwin Suryo, Tan, Owen, Norris, Murray D., Haber, Michelle, Marshall, Glenn M., Cheung, Belamy B.
Format: Artigo
Langue:Inglês
Publié: Springer US 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618413/
https://ncbi.nlm.nih.gov/pubmed/23404198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0813-y
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